Abstract: The emergence of new media has changed the main way of communication and information acquisition, and created a new path for the international communication of Chinese medicine culture. Through comparing and analyzing the top 100 popular videos about Chinese medicine culture on YouTube, we found that international audiences have a single understanding towards Chinese medicine culture with their main interest in Chinese medical treatments. However, with difficulty in converting Chinese medicine language, it is hard to communicate the theoretical connotation of Chinese medicine. In addition, due to the insufficient use of the new communication medium of social media and the particularly insufficient supply of communication contents in Chinese medicine culture, there is a lack of high-quality video resources. Therefore, regard to Chinese medicine culture, we should pay attention to its theoretical communication, and strengthen its construction of audiovisual quality content in social media through guiding and playing the main role of netizens. On top of that, we should strengthen the monitoring of public opinion towards it, and make full use of new media to make it really "go global".