Abstract: The essence of the "Statecraft and Pragmatic Application" philosophy lies in integrating scholarship with practice to address real-world issues. In the field of medicine, this translates to a close alignment between medical theory and clinical practice to enhance therapeutic efficacy. Taking Yu Jiayan's Medical Law as an example, this paper explores the influence of the "Statecraft and Pragmatic Application" philosophy on the medical ethics and conduct of Qing Dynasty physicians, revealing its unique value in the medical domain. In his work, Yu Jiayan not only discusses disease etiology and mechanisms but also elaborates on treatment methods and medical laws-standards for medical conduct-thereby embedding the "Statecraft and Pragmatic Application" philosophy into clinical practice. He advocates a medical ethic centered on "precision, benevolence, and prudence, " emphasizing the physician's social responsibility and moral cultivation. Inspired by Buddhist precepts, he establishes rules to standardize medical practice, underscoring the importance of combining theory with practice and the pivotal role of ethics in medical advancement. His ideas have had a profound impact on the development of later medical practices.