Abstract: There is a lack of attention to female substance abuse addicts at present in China, which is not only reflected in the neglect of female related health care issues and the lack of relevant theoretical research in the practice of substance rehabilitation, but also the lack of effective treatment programs specifically based on female physiological and psychological characteristics in the practice of community substance rehabilitation. By analyzing the differences between female and male substance abuse addicts, in combination with the current development of substance control social workers, and on the basis of the existing grass-roots institutions, it is proposed that as for the limited community substance rehabilitation funds, the community should absorb women's federation organizations to participate in the community substance rehabilitation. The substance control social workers combined with women's federation organizations can improve the ability to obtain resources, and the women's federation organizations should empower substance abuse addicts through professional work methods so as to explore a more effective way of substance rehabilitation for female substance abusers.