Abstract: Labor education is an important component of college and university education. In the context of the new era, the cultivation of Chinese materia medica professionals in traditional Chinese medicine universities should integrate labor education with subject education, and collaborate to cultivate high-quality professional talents. This article provides an in-depth analysis of the current problems in labor education courses. With a problem-oriented approach, it clarifies the construction ideas for labor education courses in Chinese materia medica majors, explores the construction of a goal system, content system, and evaluation system for labor education courses, pilot the construction of a campus labor education practice base, and adhere to the talent cultivation concept of "three comprehensive education", infiltrates and implements labor education in subject education, so that a new labor education system of "integrity and innovation, integration of labor and intelligence, and three-layer progress" will be constructed.This can provide reference for the establishment of labor education courses in similar universities.